Melatonin in Research: Mechanisms, Methods, and Emerging Frontiers in Chronobiology
What Is Melatonin? Biochemistry, Receptors, and Signaling in Experimental Models Melatonin is a small indoleamine synthesized from the amino acid tryptophan via serotonin, with arylalkylamine N-acetyltransferase (AANAT) and acetylserotonin O-methyltransferase (ASMT) as the key rate-limiting enzymes. While the pineal gland is the canonical source with a robust nocturnal secretion pattern, Read more…